KMID : 1149220020100020243
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Korean Journal of Oriental Medical Prescription 2002 Volume.10 No. 2 p.243 ~ p.249
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Antioxidative effects of the fermented extract of Pinus densiflora
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Mun Yeun-Ja
Lim Nan-Young Lee Sung-Won Kang Dae-Gil Baik Soon-Ki Woo Won-Hong
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Abstract
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This study was performed to investigate the effects of fermented extract of Pinus densiflora (FPD) on oxygen radicals and H2O2-induced damage. The results are as follows: 1. The 1.1-diphenyl-2-picrylhydrazyl (DPPH) free radicals were considerably reduced by FPD and IC50 value was showed the concentration of 20 §¶£¯§¢. 2. The cytotoxicity did not observe by FPD treatment in A548 cells. 3. The H2O2-induced cell damage was recovered by FPD pretreatment in A549 cells. These results suggest that FPD, as a natural antioxidant, has scavenging effect of free radicals and protection effect from H2O2-induced cytotoxicity.
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KEYWORD
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fermented extract of Pinus densiflora(FPD), oxygen radicals, H2O2-induced damage, antioxidant
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